small molecule

Trimethaphan

Synonyms/Brands: Trimetaphan, Trimethaphan, Thimethaphan, Trimetaphanum

A nicotinic antagonist that has been used as a ganglionic blocker in hypertension, as an adjunct to anesthesia, and to induce hypotension during surgery.

Molecular Formula: C₂₂H₂₅N₂OS

Molecular Weight:: 365.512

CAS:: 7187-66-8

ATC:: C02BA01

InChiKey:: CHQOEHPMXSHGCL-UHFFFAOYSA-N

InChi:: InChI=1S/C22H25N2OS/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18/h1-6,8-11,19-21H,7,12-16H2/q+1

SMILES:: O=C1N(CC2=CC=CC=C2)C2C[S+]3CCCC3C2N1CC1=CC=CC=C1

IUPAC Name:: 3,5-dibenzyl-4-oxo-8-thia-3,5-diazatricyclo[6.3.0.0,]undecan-8-ylium

DrugBank PubChem ChemSpider ChEBI

Download Curated Data for this Chemical

1104

Interactors 1
Chemical Interactions 4
Network

Chemical Summary

Trimethaphan