small molecule

Yohimbine

Synonyms/Brands: Johimbin, Yohimbin, Corynine, Yohimbine, Aphrodine, Quebrachin, Quebrachine, (+)-yohimbine, Yohimbic acid methyl ester, yohimbine hydrochloride tablet, 17alpha-Hydroxyyohimban-16alpha-carboxylic acid methyl ester, (16alpha,17alpha)-17-Hydroxyyohimban-16-carboxylic acid methyl ester

A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.

Molecular Formula: C₂₁H₂₆N₂O₃

Molecular Weight:: 354.4427

CAS:: 146-48-5

ATC:: G04BE04

InChiKey:: BLGXFZZNTVWLAY-SCYLSFHTSA-N

InChi:: InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1

SMILES:: [H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2

IUPAC Name:: methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0,.0,.0,]henicosa-2(10),4,6,8-tetraene-19-carboxylate

DrugBank ChEMBL PubChem ChemSpider ChEBI

Download Curated Data for this Chemical

1342

Interactors 18
Chemical Interactions 38
Network

Chemical Summary

Yohimbine