small molecule
Prasterone
Synonyms/Brands: DHEA, 5-DHEA, prastera, Dehydroandrosterone, Dehydroepiandrosterone, Dehydroisoandrosterone, 5-dehydroepiandrosterone, 3-hydroxyandrost-5-en-17-one, 3beta-hydroxyandrost-5-en-17-one, 3-beta-Hydroxy-5-androsten-17-one
Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion.In the United States, DHEA or DHEAS have been advertised with claims that they may be beneficial for a wide variety of ailments. DHEA and DHEAS are readily available in the United States, where they are marketed as over-the-counter dietary supplements. In November 2016, DHEA was approved (as Intrarosa) to treat women experiencing moderate to severe pain during sexual intercourse (dyspareunia), a ...
symptom of vulvar and vaginal atrophy (VVA), due to menopause.In Canada, a prescription is required to buy DHEA.
symptom of vulvar and vaginal atrophy (VVA), due to menopause.In Canada, a prescription is required to buy DHEA.
Molecular Formula: C19H28O2
Molecular Weight:: 288.4244
CAS:: 53-43-0
InChiKey:: FMGSKLZLMKYGDP-USOAJAOKSA-N
InChi:: InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1
SMILES:: [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@]([H])(O)CC[C@]12C
IUPAC Name:: (1S,2R,5S,10R,11S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0,.0,]heptadec-7-en-14-one
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- Interactors 33
- Chemical Interactions 40
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