small molecule

Staurosporine

Synonyms/Brands: 2GCD, 2DQ7, 1NVR, 1XJD, 1STC, 1U59, 1SM2, 1Q3D, 1YHS, 1XBC, S1421, CS-2716, GTPL346, DB02010, AM-2282, LS-64042, HY-15141, Q5957181, BDBM2579, EX-A1777, CGP 39360, 62996-74-1, CCG-208052, HMS3650B17, H88EPA0A3N, CCRIS 3272, ST50826371, BCPP000063, HMS1990J07, BIO1_000753 ...

Staurosporine is a cell permeable alkaloid isolated from Streptomyces staurosporeus exhibiting anti-cancer activity. Staurosporine is a potent, non-selective inhibitor of protein kinases, including protein kinase C. This agent induces apoptosis by an undetermined mechanism. (NCI)

Molecular Formula: C₂₈H₂₆N₄O₃

Molecular Weight:: 466.531

CAS:: 62996-74-1

InChiKey:: HKSZLNNOFSGOKW-UCBFMKAXSA-N

InChi:: InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20+,26-,28-/m1/s1

SMILES:: CN[C@@H]1C[C@@H]2O[C@](C)([C@@H]1OC)N1C3=C(C=CC=C3)C3=C1C1=C(C4=C(C=CC=C4)N21)C1=C3CNC1=O

IUPAC Name:: (2R,3R,4R,6S)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1,.0,.0,.0,.0,.0,]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one

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1934

Interactors 23
Chemical Interactions 37
Network

Chemical Summary

Staurosporine