small molecule

Adapalene

Synonyms/Brands: Adaferin, Adapaleno, Differine, Adapalenum, differin - gel, tactupump forte, 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid

Adapalene is a topical retinoid primarily used in the treatment of acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. It is currently marketed by Galderma under the trade names Differin in some countries, and Adaferin in India.

Molecular Formula: C₂₈H₂₈O₃

Molecular Weight:: 412.5201

CAS:: 106685-40-9

ATC:: D10AD53, D10AD03

InChiKey:: LZCDAPDGXCYOEH-UHFFFAOYSA-N

InChi:: InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)

SMILES:: COC1=C(C=C(C=C1)C1=CC2=C(C=C1)C=C(C=C2)C(O)=O)C12CC3CC(CC(C3)C1)C2

IUPAC Name:: 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid

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Download Curated Data for this Chemical

203

Interactors 6
Chemical Interactions 20
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Chemical Summary

Adapalene