small molecule

Indomethacin

Synonyms/Brands: apo , Aconip, Indocin, tivorbex, Indometacin, Indomethacin, Indometacine, Indometacina, Indometacinum, indocid cap 25mg, 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
Indomethacin is a non-steroidal antiinflammatory agent (NSAIA) with antiinflammatory, analgesic and antipyretic activity. Its pharmacological effect is thought to be mediated through inhibition of the enzyme cyclooxygenase (COX), the enzyme responsible for catalyzes the rate-limiting step in prostaglandin synthesis via the arachidonic acid pathway.
Molecular Formula: C19H16ClNO4
Molecular Weight:: 357.788
CAS:: 53-86-1
ATC:: M01AB51, S01BC01, M02AA23, S01CC02, M01AB01, C01EB03
InChiKey:: CGIGDMFJXJATDK-UHFFFAOYSA-N
InChi:: InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
SMILES:: COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O
IUPAC Name:: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
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