small molecule

Terfenadine

Synonyms/Brands: Terfnadine, Terfenadin, Terfenadina, Terfenadine, Terfenadinum, seldane 120mg once-a-day caple, (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-ol

In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.

Molecular Formula: C₃₂H₄₁NO₂

Molecular Weight:: 471.6734

CAS:: 50679-08-8

ATC:: R06AX12

InChiKey:: GUGOEEXESWIERI-UHFFFAOYSA-N

InChi:: InChI=1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35H,10,15,20-24H2,1-3H3

SMILES:: CC(C)(C)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1

IUPAC Name:: 1-(4-tert-butylphenyl)-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-ol

DrugBank BindingDB ChEMBL PubChem ChemSpider KEGG Drug

Download Curated Data for this Chemical

334

Interactors 7
Chemical Interactions 14
Network

Chemical Summary

Terfenadine