biologic
Liraglutide
Synonyms/Brands: victo, NN2211, NN-2211, Victoza, NN 2211, saxenda, NNC 90-1170, Liraglutida, Liraglutidum, xultophy 100/3.6, Liraglutide recombinant, Arg34Lys26-(N--(-Glu(N--hexadecanoyl)))-GLP-1[7-37], N-(hexadecanoyl-gamma-glutamyle)-[34-arginine]GLP-1-(7-37)-peptide, N-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptide
Victoza contains liraglutide, an analog of human GLP-1 and acts as a GLP-1 receptor agonist. The peptide precursor of liraglutide, produced by a process that includes expression of recombinant DNA in Saccharomyces cerevisiae, has been engineered to be 97% homologous to native human GLP-1 by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer on the remaining lysine residue at position 26 of the peptide precursor.
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