small molecule

Nicardipine

Synonyms/Brands: card, Cardene, Nicardipino, Nicardipinum, nicardipine hydrochloride

A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.

Molecular Formula: C₂₆H₂₉N₃O₆

Molecular Weight:: 479.525

CAS:: 55985-32-5

ATC:: C08CA04

InChiKey:: ZBBHBTPTTSWHBA-UHFFFAOYSA-N

InChi:: InChI=1S/C26H29N3O6/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19/h5-12,15,24,27H,13-14,16H2,1-4H3

SMILES:: COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OCCN(C)CC1=CC=CC=C1

IUPAC Name:: 3-{2-[benzyl(methyl)amino]ethyl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

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Download Curated Data for this Chemical

612

Interactors 15
Chemical Interactions 15
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Chemical Summary

Nicardipine