small molecule

Trazodone

Synonyms/Brands: ratio-, Trazodone, Trazodona, Trazodonum, penta-trazodone tablets, 2-(3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)

Molecular Formula: C₁₉H₂₂ClN₅O

Molecular Weight:: 371.864

CAS:: 19794-93-5

ATC:: N06AX05

InChiKey:: PHLBKPHSAVXXEF-UHFFFAOYSA-N

InChi:: InChI=1S/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2

SMILES:: ClC1=CC=CC(=C1)N1CCN(CCCN2N=C3C=CC=CN3C2=O)CC1

IUPAC Name:: 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one

DrugBank ChEMBL PubChem ChemSpider ChEBI

Download Curated Data for this Chemical

646

Interactors 7
Chemical Interactions 19
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Chemical Summary

Trazodone