small molecule

Epinastine

Synonyms/Brands: elest, Epinastin, Epinastine, Epinastina, Epinastinum, (+-)-Epinastine, epinastine hydrochloride, 3-amino-9,13b-dihydro-1H-Dibenz(c,F)imidazo(1,5-a)azepine
Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory chemical mediators from the blood vessel to halt progression of the allergic response.
Molecular Formula: C16H15N3
Molecular Weight:: 249.3104
CAS:: 80012-43-7
ATC:: R06AX24, S01GX10
InChiKey:: WHWZLSFABNNENI-UHFFFAOYSA-N
InChi:: InChI=1S/C16H15N3/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16/h1-8,15H,9-10H2,(H2,17,18)
SMILES:: NC1=NCC2N1C1=CC=CC=C1CC1=CC=CC=C21
IUPAC Name:: 2,4-diazatetracyclo[12.4.0.0,.0,]octadeca-1(18),3,7,9,11,14,16-heptaen-3-amine
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  • Interactors 6
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