small molecule

Tretinoin

Synonyms/Brands: ATRA, viti, Renova, Eudyna, Solage, Retin-a, Vesanoid, Stieva-a, Tretin m, Vitinoin, Trtinone, Retisol-a, Ro 1-5488, Tretinoin, Tretinoina, AGN 100335, Tretinoinum, Retionic Acid, RETINOIC acid, Vitamin A acid, beta-Retinoic acid, all-trans-Tretinoin, trans-Retinoic acid, all-(e)-Retinoic acid, All Trans Retinoic Acid, All Trans-Retinoic Acid, all-trans-Retinoic acid, all-trans-Vitamin a acid, all-trans-Vitamin a1 acid, tretinoin gel microsphere ...

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as tretinoin are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).

Molecular Formula: C₂₀H₂₈O₂

Molecular Weight:: 300.4351

CAS:: 302-79-4

ATC:: L01XX14, D10AD01, D10AD51

InChiKey:: SHGAZHPCJJPHSC-YCNIQYBTSA-N

InChi:: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+

SMILES:: CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O

IUPAC Name:: 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid

DrugBank ChEMBL PubChem ChemSpider ChEBI KEGG Drug

Download Curated Data for this Chemical

745

Interactors 9
Chemical Interactions 34
Network

Chemical Summary

Tretinoin