small molecule

Propiomazine

Synonyms/Brands: Propiomazin, Propiomazine, Propiomazina, Propiomazinum, 3-Propionyl-10-dimethylaminoisopropylphenothiazine, 10-(2-Dimethylaminopropyl)-2-propionylphenothiazine, 2-Propionyl-10-(2-(dimethylamino)propyl)phenothiazine

Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. Future uses may include the treatment of obsessive-compulsive disorder and severe behavioral disorders in autism. Structurally and pharmacologically similar to clozapine, propiomazine binds to alpha(1), dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors.

Molecular Formula: C₂₀H₂₄N₂OS

Molecular Weight:: 340.482

CAS:: 362-29-8

ATC:: N05CM06

InChiKey:: UVOIBTBFPOZKGP-UHFFFAOYSA-N

InChi:: InChI=1S/C20H24N2OS/c1-5-18(23)15-10-11-20-17(12-15)22(13-14(2)21(3)4)16-8-6-7-9-19(16)24-20/h6-12,14H,5,13H2,1-4H3

SMILES:: CCC(=O)C1=CC2=C(SC3=CC=CC=C3N2CC(C)N(C)C)C=C1

IUPAC Name:: 1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}propan-1-one

DrugBank ChEMBL PubChem ChemSpider ChEBI KEGG Drug

Download Curated Data for this Chemical

767

Interactors 14
Chemical Interactions 30
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Chemical Summary

Propiomazine