small molecule
Eflornithine
Synonyms/Brands: DFMO, vaniqa, -difluoromethylornithine, (RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid
Eflornithine is a prescription drug indicated in the treatment of facial hirsutism (excessive hair growth). Eflornithine hydrochloride cream for topical application is intended for use in women suffering from facial hirsutism and is sold by Allergan, Inc. under the brand name Vaniqa. Besides being a non-mechanical and non-cosmetic treatment, eflornithine is the only non-hormonal and non-systemic prescription option available for women who suffer from facial hirsutism. Eflornithine for injection against sleeping sickness was manufactured by Sanofi Aventis and sold under the brand name Ornidyl in the USA. It is now discontinued. Eflornithine is on the World Health Organization's List of Essential Medicines.
Molecular Formula: C6H12F2N2O2
Molecular Weight:: 182.171
CAS:: 70052-12-9
InChiKey:: VLCYCQAOQCDTCN-UHFFFAOYSA-N
InChi:: InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12)
SMILES:: NCCCC(N)(C(F)F)C(O)=O
IUPAC Name:: 2,5-diamino-2-(difluoromethyl)pentanoic acid
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