small molecule

Armodafinil

Synonyms/Brands: nuvigil, R-modafinil, armodafinil, ()-2-[(R)-(diphenylmethyl)sulfinyl]acetamide
Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the ()-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. (a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.
Molecular Formula: C15H15NO2S
Molecular Weight:: 273.35
ATC:: N06BA13
InChiKey:: YFGHCGITMMYXAQ-LJQANCHMSA-N
InChi:: InChI=1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)/t19-/m1/s1
SMILES:: NC(=O)C[S@@](=O)C(C1=CC=CC=C1)C1=CC=CC=C1
IUPAC Name:: 2-[(R)-diphenylmethanesulfinyl]acetamide
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