small molecule

Progabide

Synonyms/Brands: Progabida, Progabide, Progabidum, Halogabide

Progabide is an analog and prodrug of gamma-aminobutyric acid. It is commonly used in the treatment of epilepsy. It has agonistic activity for both the GABAA and GABAB receptors. Progabide has been investigated for many diseases besides epilepsy, including Parkinson's disease, schizophrenia, clinical depression and anxiety disorder with varying success.

Molecular Formula: C₁₇H₁₆ClFN₂O₂

Molecular Weight:: 334.78

CAS:: 62666-20-0

ATC:: N03AG05

InChiKey:: IBALRBWGSVJPAP-FXBPSFAMSA-N

InChi:: InChI=1S/C17H16ClFN2O2/c18-12-5-3-11(4-6-12)17(21-9-1-2-16(20)23)14-10-13(19)7-8-15(14)22/h3-8,10,22H,1-2,9H2,(H2,20,23)/b21-17-

SMILES:: OC(=N)CCC\N=C(\C1=CC=C(Cl)C=C1)C1=C(O)C=CC(F)=C1

IUPAC Name:: 4-[(Z)-[(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylidene]amino]butanimidic acid

DrugBank ChEMBL KEGG Drug

Download Curated Data for this Chemical

827

Interactors 2
Chemical Interactions 8
Network

Chemical Summary

Progabide