small molecule

Terbinafine

Synonyms/Brands: Terbinafina, Terbinafinum, goodsense te, kroger antifungal, (e)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine, (e)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (squalene 2,3-epoxidase), an enzyme that is part of the fungal cell wall synthesis pathway.
Molecular Formula: C21H25N
Molecular Weight:: 291.4299
CAS:: 91161-71-6
ATC:: D01BA02, D01AE15
InChiKey:: DOMXUEMWDBAQBQ-WEVVVXLNSA-N
InChi:: InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+
SMILES:: CN(C\C=C\C#CC(C)(C)C)CC1=CC=CC2=CC=CC=C12
IUPAC Name:: [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)(naphthalen-1-ylmethyl)amine
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