small molecule

Tipranavir

Synonyms/Brands: aptivus

Tipranavir is a sulfonamide-containing dyhydropyrone and a nonpeptidic protease inhibitor that targets the HIV protease. It is administered with ritonavir in combination therapy to treat HIV infections.

Molecular Formula: C₃₁H₃₃F₃N₂O₅S

Molecular Weight:: 602.664

CAS:: 174484-41-4

ATC:: J05AE09

InChiKey:: SUJUHGSWHZTSEU-FYBSXPHGSA-N

InChi:: InChI=1S/C31H33F3N2O5S/c1-3-16-30(17-15-21-9-6-5-7-10-21)19-26(37)28(29(38)41-30)25(4-2)22-11-8-12-24(18-22)36-42(39,40)27-14-13-23(20-35-27)31(32,33)34/h5-14,18,20,25,36-37H,3-4,15-17,19H2,1-2H3/t25-,30-/m1/s1

SMILES:: [H][C@@](CC)(C1=CC(NS(=O)(=O)C2=NC=C(C=C2)C(F)(F)F)=CC=C1)C1=C(O)C[C@@](CCC)(CCC2=CC=CC=C2)OC1=O

IUPAC Name:: N-{3-[(1R)-1-[(6R)-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-5,6-dihydro-2H-pyran-3-yl]propyl]phenyl}-5-(trifluoromethyl)pyridine-2-sulfonamide

DrugBank BindingDB PDB ChEMBL ChEBI

Download Curated Data for this Chemical

922

Interactors 1
Chemical Interactions 8
Network

Chemical Summary

Tipranavir