Related Resources
The BioGRID Open Respository of CRISPR Screens (ORCS) is a publicly accessible database of CRISPR screens compiled through comprehensive curation of all genome-wide CRISPR screen data reported in the biomedical literature. ORCS is updated on a quarterly basis and is fully searchable by gene/protein, phenotype, cell line, authors, and other attributes. Each screen recorded in ORCS is accompanied by structured metadata annotation that captures salient CRISPR experimental details. All data in ORCS can be downloaded in standard formats.
BioGRID themed curation projects focus on specific biological processes with disease relevance. Core genes/proteins central to the process are assembled with expert input and relevant publications curated for biological interactions. Themed curation projects are updated monthly and additional projects are generated on a regular basis.
See current projects on Synthetic Protein Interaction Project, Human Papilloma Virus (HPV), Autism spectrum disorder, Alzheimer's Disease, COVID-19 Coronavirus, Fanconi Anemia, Glioblastoma, the Yeast Kinome, the Ubiquitin-Proteasome System and Autophagy. If you would like to suggest or participate in a new themed project, please contact support@thebiogrid.org
GIX is a browser extension that allows you to retrieve information about a gene product directly on any webpage simply by double clicking an official gene name, synonym or supported accession.
Partners
Latest News
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 87,069 publications. These additions bring our total number of non-redundant interactions to 2,219,787, raw interactions to 2,862,647, non-redundant chemical associations to 14,024, raw chemical associations to 31,540, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 86,799 publications. These additions bring our total number of non-redundant interactions to 2,210,546, raw interactions to 2,851,050, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 86,637 publications. These additions bring our total number of non-redundant interactions to 2,206,026, raw interactions to 2,844,981, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 86,536 publications. These additions bring our total number of non-redundant interactions to 2,203,605, raw interactions to 2,840,984, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 86,477 publications. These additions bring our total number of non-redundant interactions to 2,201,055, raw interactions to 2,837,675, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID ORCS curated CRISPR database has been updated to include CRISPR screens from a total of 382 different publications. These additions bring the total number of curated CRISPR screens in our database to 2,134 encompassing 93,295 genes, 809 different cell lines, 137 different cell types, and 29 different phenotypes across 5 different organisms (Budding Yeast, Human, Mouse, African Green Monkey, and Fruit Fly).
New curated data are added to our CRISPR Database in curation updates on a regular basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these CRISPR data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 86,339 publications. These additions bring our total number of non-redundant interactions to 2,199,035, raw interactions to 2,834,410, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 86,161 publications. These additions bring our total number of non-redundant interactions to 2,194,102, raw interactions to 2,826,897, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 86,032 publications. These additions bring our total number of non-redundant interactions to 2,192,664, raw interactions to 2,824,633, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 85,855 publications. These additions bring our total number of non-redundant interactions to 2,189,120, raw interactions to 2,818,695, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.