The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 64,826 publications. These additions bring our total number of non-redundant interactions to 1,202,227, raw interactions to 1,548,143, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.
Welcome to the Biological General Repository for Interaction Datasets
BioGRID is an interaction repository with data compiled through comprehensive curation efforts. Our current index is version 3.4.160 and searches 64,981 publications for 1,553,656 protein and genetic interactions, 27,785 chemical associations and 39,028 post translational modifications from major model organism species. All data are freely provided via our search index and available for download in standardized formats.
Search the BioGRID
Search by identifiers, keywords, and gene names...
Search by pubmed ids or keywords in title/abstract/mesh terms...
Areas of Interest to Help You Get Started
Build and Download Interaction Datasets
Create custom interaction datasets by protein or by publication. You can also download our entire dataset in a wide variety of standard formats.
Link To Us or Submit Interactions
Send us your datasets or link to the BioGRID directly from your own website or database. Full details on how to contribute are available here.
Online Tools and Resources
We've developed tools that make use of BioGRID data. Check out the list of tools to see if we can help you work with our data.
View Our Interaction Statistics
Find out how many organisms, proteins, publications, and interactions are available in the current release of the BioGRID.
Latest Updates
Latest News
The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 64,583 publications. These additions bring our total number of non-redundant interactions to 1,201,148, raw interactions to 1,546,181, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.
Posted: March 1, 2018 - 5:59 am
The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 64,317 publications. These additions bring our total number of non-redundant interactions to 1,197,407, raw interactions to 1,540,934, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.
Posted: February 1, 2018 - 2:18 am
The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 64,134 publications. These additions bring our total number of non-redundant interactions to 1,193,809, raw interactions to 1,536,533, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.
Posted: January 1, 2018 - 6:18 am
The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 63,959 publications. These additions bring our total number of non-redundant interactions to 1,168,521, raw interactions to 1,507,991, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.
Posted: December 1, 2017 - 3:15 am
The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 63,848 publications. These additions bring our total number of non-redundant interactions to 1,167,125, raw interactions to 1,505,899, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.
Posted: November 1, 2017 - 4:44 am
The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 63,683 publications. These additions bring our total number of non-redundant interactions to 1,162,605, raw interactions to 1,499,723, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.
Posted: October 1, 2017 - 3:21 am
The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 63,487 publications. These additions bring our total number of non-redundant interactions to 1,158,978, raw interactions to 1,495,320, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.
Posted: September 1, 2017 - 4:03 am
The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 63,354 publications. These additions bring our total number of non-redundant interactions to 1,158,266, raw interactions to 1,493,749, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.
Posted: August 1, 2017 - 3:27 am
BioGRID update 3.4.150 includes a comprehensive update to our Drosophila melanogaster (Fruit Fly) dataset in partnership with FlyBase.org. This update verifies and validates more than 48,000 existing interactions and incorporates an additional 19,000+ new interactions across more than 6,100 total publications. This update also increases the total number of Drosophila melanogaster interactions deposited in BioGRID to 67,932. These interactions and all associated meta data are available immediately online via all standard BioGRID searches and supported download formats. You can also find them available at FlyBase.org in all search result pages and in FlyBase.org download files.
A special thanks to the entire FlyBase Consortium for their tireless curation efforts and in particular Gil dos Santos for directly helping facilitate the BioGRID collaboration.
If you have an interaction dataset you'd like to deposit directly into the BioGRID, please contact us at biogridadmin@gmail.com.
Posted: July 10, 2017 - 5:14 pm