BAIT
YES1
HsT441, P61-YES, Yes, c-yes
YES proto-oncogene 1, Src family tyrosine kinase
GO Process (12)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- T cell costimulation [TAS]
- blood coagulation [TAS]
- cell differentiation [IBA]
- cellular protein modification process [TAS]
- cellular response to peptide hormone stimulus [IBA]
- innate immune response [IBA, TAS]
- leukocyte migration [TAS]
- peptidyl-tyrosine autophosphorylation [IBA]
- regulation of cell proliferation [IBA]
- regulation of vascular permeability [TAS]
- transmembrane receptor protein tyrosine kinase signaling pathway [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SPRR2A
small proline-rich protein 2A
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes.
Deficient biliary epithelial cell (BEC) expression of small proline-rich protein (SPRR) 2A in IL-6(-/-) mice is associated with defective biliary barrier function after bile duct ligation. And numerous gene array expression studies show SPRR2A to commonly be among the most highly up-regulated genes in many non-squamous, stressed and remodeling barrier epithelia. Since the function of SPRR in these circumstances is ... [more]
J. Hepatol. Feb. 01, 2008; 48(2);276-88 [Pubmed: 18155796]
Throughput
- Low Throughput
Curated By
- BioGRID