EFNB1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
EPHB1
Gene Ontology Biological Process
- angiogenesis [ISO]
- axon guidance [IDA, IMP]
- camera-type eye morphogenesis [IMP]
- cell chemotaxis [IMP, ISO]
- cell-substrate adhesion [ISO]
- central nervous system projection neuron axonogenesis [IDA, IMP]
- cranial nerve development [IMP]
- dendritic spine development [IMP, ISO]
- dendritic spine morphogenesis [IMP]
- detection of temperature stimulus involved in sensory perception of pain [IMP]
- ephrin receptor signaling pathway [IDA, ISO, TAS]
- establishment of cell polarity [IMP]
- immunological synapse formation [ISO]
- neural precursor cell proliferation [IMP]
- neurogenesis [IMP]
- optic nerve morphogenesis [IMP]
- peptidyl-tyrosine phosphorylation [ISO, TAS]
- positive regulation of synapse assembly [IMP]
- protein autophosphorylation [ISO]
- regulation of ERK1 and ERK2 cascade [ISO]
- regulation of JNK cascade [ISO]
- regulation of neuron death [ISO]
- retinal ganglion cell axon guidance [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Luminescence
An interaction is inferred when a bait protein, tagged with luciferase, is enzymatically detected in immunoprecipitates of the prey protein as light emission. The prey protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag.
Publication
Similarities and Differences in the Way Transmembrane-Type Ligands Interact with the Elk Subclass of Eph Receptors
The Eph family of receptor tyrosine kinases and their cell surface bound ligands have been implicated in a number of developmental processes, including axon pathfinding and fasciculation, as well as patterning in the central nervous system. To better understand the complex signaling events taking place, we have undertaken a comparative analysis of ligand-receptor interactions between a subset of ligands, those ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| EPHB1 EFNB1 | Affinity Capture-Luminescence Affinity Capture-Luminescence An interaction is inferred when a bait protein, tagged with luciferase, is enzymatically detected in immunoprecipitates of the prey protein as light emission. The prey protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag. | Low | - | BioGRID | - |
Curated By
- BioGRID