BAIT
SGF73
SPCC126.04c
SAGA complex subunit Sgf73
GO Process (6)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
RAP1
SPBC1778.02
telomere binding protein Rap1
GO Process (9)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- chromatin silencing at telomere [IMP]
- meiotic telomere clustering [IMP]
- negative regulation of telomere maintenance via telomerase [IGI]
- negative regulation of telomeric RNA transcription from RNA pol II promoter [IMP]
- protection from non-homologous end joining at telomere [IGI, IMP]
- regulation of transcription from RNA polymerase II promoter [ISS]
- telomere maintenance [IGI]
- telomeric 3' overhang formation [IGI]
- transcription from RNA polymerase II promoter [ISO, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Negative Genetic
Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores.
Publication
Large scale screening of genetic interaction with sgf73(+) in fission yeast.
Genetic interaction (GI) not only suggests functional correlations between different genes in vivo, but also provides clues for understanding the potential biological function of a specific gene. Screening of GI is an important method for understanding GI between different genes. In this study, we selected sgf73⺠as a query, which encodes a subunit of SAGA (Spt-Ada-Gcn5 acetyltransferase) complex deubiquitination module, ... [more]
Yi Chuan Jul. 01, 2014; 36(7);723-31 [Pubmed: 25076038]
Throughput
- High Throughput
Additional Notes
- validated by low throughput assay.
Curated By
- BioGRID