BAIT
SGF73
SPCC126.04c
SAGA complex subunit Sgf73
GO Process (6)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
UBR1
SPBC32F12.14, SPBC19C7.02
N-end-recognizing protein, UBR ubiquitin-protein ligase E3 Ubr1
GO Process (7)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- cellular response to hyperoxia [IMP]
- negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels [IDA]
- negative regulation of transcription by transcription factor catabolism [IMP]
- proteasome localization [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IMP]
- protein ubiquitination [IMP]
- regulation of filamentous growth [IMP]
Gene Ontology Molecular Function
Schizosaccharomyces pombe (972h)
Negative Genetic
Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores.
Publication
Large scale screening of genetic interaction with sgf73(+) in fission yeast.
Genetic interaction (GI) not only suggests functional correlations between different genes in vivo, but also provides clues for understanding the potential biological function of a specific gene. Screening of GI is an important method for understanding GI between different genes. In this study, we selected sgf73⺠as a query, which encodes a subunit of SAGA (Spt-Ada-Gcn5 acetyltransferase) complex deubiquitination module, ... [more]
Yi Chuan Jul. 01, 2014; 36(7);723-31 [Pubmed: 25076038]
Throughput
- High Throughput
Additional Notes
- validated by low throughput assay.
Curated By
- BioGRID