BAIT
SGF73
SPCC126.04c
SAGA complex subunit Sgf73
GO Process (6)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
SDS23
moc1, psp1, SPBC646.13
PP2A-type phosphatase inhibitor Sds23/Moc1
GO Process (10)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- cAMP-mediated signaling [IGI]
- cellular response to glucose starvation [IMP]
- cellular response to salt stress [IMP]
- negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity [IMP]
- negative regulation of protein dephosphorylation [IDA]
- positive regulation of conjugation with cellular fusion [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of protein phosphorylation [IMP]
- regulation of conjugation with cellular fusion [IGI]
- regulation of mitotic cell cycle [IMP]
Gene Ontology Molecular Function
Schizosaccharomyces pombe (972h)
Negative Genetic
Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores.
Publication
Large scale screening of genetic interaction with sgf73(+) in fission yeast.
Genetic interaction (GI) not only suggests functional correlations between different genes in vivo, but also provides clues for understanding the potential biological function of a specific gene. Screening of GI is an important method for understanding GI between different genes. In this study, we selected sgf73⺠as a query, which encodes a subunit of SAGA (Spt-Ada-Gcn5 acetyltransferase) complex deubiquitination module, ... [more]
Yi Chuan Jul. 01, 2014; 36(7);723-31 [Pubmed: 25076038]
Throughput
- High Throughput
Additional Notes
- validated by low throughput assay.
Curated By
- BioGRID