SAGA complex subunit Sgf73
Schizosaccharomyces pombe (972h)


TIM22 inner membrane protein import complex subunit Tim13 (predicted)
GO Process (1)
GO Function (1)
GO Component (4)
Schizosaccharomyces pombe (972h)

Negative Genetic

Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores.


Large scale screening of genetic interaction with sgf73(+) in fission yeast.

Guo Y, Lei B, Deng X, Yu Y, Lv H

Genetic interaction (GI) not only suggests functional correlations between different genes in vivo, but also provides clues for understanding the potential biological function of a specific gene. Screening of GI is an important method for understanding GI between different genes. In this study, we selected sgf73⁺ as a query, which encodes a subunit of SAGA (Spt-Ada-Gcn5 acetyltransferase) complex deubiquitination module, ... [more]

Yi Chuan Jul. 01, 2014; 36(7);723-31 [Pubmed: 25076038]


  • High Throughput

Additional Notes

  • validated by low throughput assay.

Curated By

  • BioGRID