BAIT

KMS2

SPBC947.12
spindle pole body protein Kms2
GO Process (3)
GO Function (1)
GO Component (5)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Schizosaccharomyces pombe (972h)
PREY

PCP1

SPAC6G9.06c
pericentrin Pcp1
GO Process (3)
GO Function (1)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Schizosaccharomyces pombe (972h)

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

The KASH protein Kms2 coordinates mitotic remodeling of the spindle pole body.

Waelde S, King MC

Defects in the biogenesis of the spindle pole body (SPB), the yeast centrosome equivalent, can lead to monopolar spindles and mitotic catastrophe. The KASH domain protein Kms2 and the SUN domain protein Sad1 colocalize within the nuclear envelope at the site of SPB attachment during interphase and at the spindle poles during mitosis in Schizosaccharomyces pombe. We show that Kms2 ... [more]

J. Cell. Sci. Aug. 15, 2014; 127(0);3625-40 [Pubmed: 24963130]

Throughput

  • Low Throughput

Additional Notes

  • Figure 4
  • Table S1
  • identified by mass spec

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
KMS2 PCP1
Synthetic Lethality
Synthetic Lethality

A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.

Low-BioGRID
1023414

Curated By

  • BioGRID