BAIT
RED1
iss3, SPAC1006.03c
RNA elimination defective protein Red1
GO Process (5)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
USP101
snp1, SPAC19A8.13
U1 snRNP-associated protein Usp101
GO Process (2)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Schizosaccharomyces pombe (972h)
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.
RNA is a central component of gene-silencing pathways that regulate diverse cellular processes. In the fission yeast Schizosaccharomyces pombe, an RNA-based mechanism represses meiotic gene expression during vegetative growth. This pathway depends on the zinc finger protein Red1, which is required to degrade meiotic mRNAs as well as to target histone H3 lysine 9 (H3K9) methylation, a repressive chromatin mark, ... [more]
RNA Apr. 08, 2014; 0(0); [Pubmed: 24713849]
Quantitative Score
- 7.662835249 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- C-terminally 3xFLAG-tagged SPAC1006.03c
Curated By
- BioGRID