RED1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
POB3
Gene Ontology Biological Process
- cellular protein localization [IMP]
- chromatin silencing at centromere [IMP]
- chromatin silencing at silent mating-type cassette [IMP]
- histone exchange [IC]
- mitotic sister chromatid segregation [IMP]
- nucleosome assembly [ISO]
- positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.
RNA is a central component of gene-silencing pathways that regulate diverse cellular processes. In the fission yeast Schizosaccharomyces pombe, an RNA-based mechanism represses meiotic gene expression during vegetative growth. This pathway depends on the zinc finger protein Red1, which is required to degrade meiotic mRNAs as well as to target histone H3 lysine 9 (H3K9) methylation, a repressive chromatin mark, ... [more]
Quantitative Score
- 5.859375 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- C-terminally 3xFLAG-tagged SPAC1006.03c
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| POB3 RED1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -8.2607 | BioGRID | 794753 |
Curated By
- BioGRID