BAIT
RED5
SPBC337.12, SPBC337.12
human ZC3H3 homolog
GO Process (2)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
RFC2
SPAC23D3.02
DNA replication factor C complex subunit Rfc2
GO Process (2)
GO Function (1)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.
RNA is a central component of gene-silencing pathways that regulate diverse cellular processes. In the fission yeast Schizosaccharomyces pombe, an RNA-based mechanism represses meiotic gene expression during vegetative growth. This pathway depends on the zinc finger protein Red1, which is required to degrade meiotic mRNAs as well as to target histone H3 lysine 9 (H3K9) methylation, a repressive chromatin mark, ... [more]
RNA Apr. 08, 2014; 0(0); [Pubmed: 24713849]
Quantitative Score
- 14.70588235 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- C-terminally 3xFLAG-tagged SPBC337.12
Curated By
- BioGRID