Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays.

Grelle G, Kostka S, Otto A, Kersten B, Genser KF, Mueller EC, Waelter S, Boeddrich A, Stelzl U, Haenig C, Volkmer-Engert R, Landgraf C, Alberti S, Hoehfeld J, Stroedicke M, Wanker EE

Proteins mediate their biological function through interactions with other proteins. Therefore, the systematic identification and characterization of protein-protein interactions have become a powerful proteomic strategy to understand protein function and comprehensive cellular regulatory networks. For the screening of valosin-containing protein, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners, we utilized a membrane-based array technology that allows the ... [more]

Mol. Cell Proteomics Feb. 01, 2006; 5(2);234-44 [Pubmed: 16275660]

Throughput

  • Low Throughput

Additional Notes

  • Peptide array

Curated By

  • BioGRID