BAIT

LRRC41

AA409966, AW555107, D630045E04Rik, D730026A16Rik, MUF1, RP23-383D12.7
leucine rich repeat containing 41
GO Process (0)
GO Function (2)
GO Component (3)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus
PREY

LRRC41

AA409966, AW555107, D630045E04Rik, D730026A16Rik, MUF1, RP23-383D12.7
leucine rich repeat containing 41
GO Process (0)
GO Function (2)
GO Component (3)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

MUF1/Leucine-Rich Repeat Containing 41 (LRRC41), a Substrate of RhoBTB-Dependent Cullin 3 Ubiquitin Ligase Complexes, Is a Predominantly Nuclear Dimeric Protein.

Schenkova K, Lutz J, Kopp M, Ramos S, Rivero F

RhoBTB (BTB stands for broad-complex, tramtrack, bric a brac) proteins are tumor suppressors involved in the formation of cullin 3 (Cul3)-dependent ubiquitin ligase complexes. However, no substrates of RhoBTB-Cul3 ubiquitin ligase complexes have been identified. We identified MUF1 (LRRC41, leucine-rich repeat containing 41) as a potential interaction partner of RhoBTB3 in a two-hybrid screening on a mouse brain cDNA library. ... [more]

Unknown Jun. 15, 2012; 0(0); [Pubmed: 22709582]

Throughput

  • Low Throughput

Curated By

  • BioGRID