BAIT

CACNA1G

Ca(V)T.1, Cav3.1, NBR13
calcium channel, voltage-dependent, T type, alpha 1G subunit
Homo sapiens
PREY

RANBP9

BPM-L, BPM90, RANBPM, RanBP7
RAN binding protein 9
GO Process (3)
GO Function (3)
GO Component (3)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Modulation of Ca(v)3.1 T-type Ca2+ channels by the ran binding protein RanBPM.

Kim T, Kim S, Yun HM, Chung KC, Han YS, Shin HS, Rhim H

In order to study the currently unknown cellular signaling pathways of Ca(v)3.1 T-type Ca(2+) channels (Ca(v)3.1 channels), we performed a yeast two-hybrid screening using intracellular domains of Ca(v)3.1 alpha1 subunit as bait. After screening the human brain cDNA library, several proteins, including RanBPM, were identified as interacting with Ca(v)3.1 channels. RanBPM was found to bind to the cytoplasmic intracellular loop ... [more]

Biochem. Biophys. Res. Commun. Jan. 02, 2009; 378(1);15-20 [Pubmed: 18801335]

Throughput

  • Low Throughput

Curated By

  • BioGRID