CD81
Gene Ontology Biological Process
- activation of MAPK activity [ISO]
- phosphatidylinositol biosynthetic process [ISO]
- phosphatidylinositol metabolic process [ISO]
- positive regulation of 1-phosphatidylinositol 4-kinase activity [ISO]
- positive regulation of B cell proliferation [TAS]
- positive regulation of cell growth [TAS]
- positive regulation of cell proliferation [ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [ISO]
- protein localization [ISO]
- regulation of cell motility [IGI]
- regulation of cell proliferation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
IFITM2
Gene Ontology Biological Process
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Expression of the mouse fragilis gene products in immune cells and association with receptor signaling complexes.
The mouse genome possesses five genes encoding proteins homologous to human Leu-13. The Leu-13 protein associates with immune cell receptor activation complexes: a monoclonal antibody against Leu-13 induces T and B cells to form homotypic aggregates, inhibits activation-induced proliferation and induces the shedding of L-selectin. The mouse fragilis proteins have not been previously analyzed as components of the immune response. ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID