FKBP1B
Gene Ontology Biological Process
- 'de novo' protein folding [TAS]
- calcium ion transmembrane transport [TAS]
- calcium-mediated signaling using intracellular calcium source [TAS]
- cell communication by electrical coupling involved in cardiac conduction [TAS]
- chaperone-mediated protein folding [IBA]
- cytosolic calcium ion homeostasis [IDA, IGI]
- negative regulation of heart rate [ISS]
- negative regulation of protein phosphatase type 2B activity [IDA]
- negative regulation of release of sequestered calcium ion into cytosol [IDA]
- negative regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- positive regulation of sequestering of calcium ion [IDA]
- protein maturation by protein folding [TAS]
- protein peptidyl-prolyl isomerization [IDA]
- protein refolding [TAS]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [IBA, ISS]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [IDA]
- regulation of ryanodine-sensitive calcium-release channel activity [IDA, IMP]
- response to redox state [IDA]
Gene Ontology Molecular Function
KRT31
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A proteome-scale map of the human interactome network.
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ?30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
KRT31 FKBP1B | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 2703616 |
Curated By
- BioGRID