BAIT
PIM1
PIM
Pim-1 proto-oncogene, serine/threonine kinase
GO Process (8)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
- cell proliferation [IDA]
- multicellular organismal development [TAS]
- negative regulation of apoptotic process [IDA]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [IDA]
- protein autophosphorylation [IDA, IMP]
- protein phosphorylation [IDA]
- regulation of mitotic cell cycle [IBA]
Gene Ontology Molecular Function
Homo sapiens
PREY
FXR2
FMR1L2, FXR2P
fragile X mental retardation, autosomal homolog 2
GO Process (1)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A proteome-scale map of the human interactome network.
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ?30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently ... [more]
Cell Nov. 20, 2014; 159(5);1212-26 [Pubmed: 25416956]
Throughput
- High Throughput
Curated By
- BioGRID