BHLHE40
Gene Ontology Biological Process
- circadian regulation of gene expression [IDA]
- entrainment of circadian clock by photoperiod [ISS]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- regulation of transcription, DNA-templated [NAS]
- transcription from RNA polymerase II promoter [IDA, ISS]
Gene Ontology Molecular Function- E-box binding [IDA]
- MRF binding [ISS]
- RNA polymerase II activating transcription factor binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISS]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [IDA]
- bHLH transcription factor binding [IPI]
- protein binding [IPI]
- protein domain specific binding [IPI]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription corepressor activity [IDA]
- E-box binding [IDA]
- MRF binding [ISS]
- RNA polymerase II activating transcription factor binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISS]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [IDA]
- bHLH transcription factor binding [IPI]
- protein binding [IPI]
- protein domain specific binding [IPI]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription corepressor activity [IDA]
Gene Ontology Cellular Component
VAC14
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A proteome-scale map of the human interactome network.
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ?30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| VAC14 BHLHE40 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 2707834 |
Curated By
- BioGRID