BAIT
AKAP9
AKAP-9, AKAP350, AKAP450, CG-NAP, HYPERION, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO
A kinase (PRKA) anchor protein 9
GO Process (10)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- cellular response to cAMP [IMP]
- mitotic cell cycle [TAS]
- positive regulation of peptidyl-serine phosphorylation [IMP]
- positive regulation of potassium ion transmembrane transporter activity [IMP]
- regulation of heart rate by cardiac conduction [IMP]
- regulation of membrane repolarization [IMP]
- regulation of ventricular cardiac muscle cell membrane repolarization [IMP]
- synaptic transmission [TAS]
- transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
WAC
BM-016, PRO1741, Wwp4, RP11-48B24.1
WW domain containing adaptor with coiled-coil
GO Process (7)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- G1 DNA damage checkpoint [IMP]
- cellular response to DNA damage stimulus [IMP]
- histone H2B conserved C-terminal lysine ubiquitination [IMP]
- histone monoubiquitination [IMP]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- positive regulation of macroautophagy [IMP]
- positive regulation of transcription, DNA-templated [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA]
- nucleus [TAS]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A proteome-scale map of the human interactome network.
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ?30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently ... [more]
Cell Nov. 20, 2014; 159(5);1212-26 [Pubmed: 25416956]
Throughput
- High Throughput
Curated By
- BioGRID