BAIT
RBPMS
HERMES
RNA binding protein with multiple splicing
GO Process (3)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
HEY2
CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32, RP1-293L8.3
hes-related family bHLH transcription factor with YRPW motif 2
GO Process (34)
GO Function (9)
GO Component (5)
Gene Ontology Biological Process
- Notch signaling involved in heart development [IC]
- Notch signaling pathway [ISS, TAS]
- arterial endothelial cell differentiation [ISS]
- ascending aorta morphogenesis [ISS]
- atrial septum morphogenesis [ISS]
- cardiac epithelial to mesenchymal transition [ISS]
- cardiac left ventricle morphogenesis [ISS]
- cardiac right ventricle morphogenesis [ISS]
- cardiac septum morphogenesis [ISS]
- cardiac ventricle morphogenesis [ISS]
- dorsal aorta morphogenesis [ISS]
- labyrinthine layer blood vessel development [ISS]
- mesenchymal cell development [ISS]
- muscular septum morphogenesis [ISS]
- negative regulation of cardiac vascular smooth muscle cell differentiation [ISS]
- negative regulation of gene expression [ISS]
- negative regulation of transcription by transcription factor localization [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation [ISS]
- negative regulation of transcription initiation from RNA polymerase II promoter [IDA]
- negative regulation of transcription regulatory region DNA binding [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- outflow tract morphogenesis [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- pulmonary artery morphogenesis [ISS]
- pulmonary valve morphogenesis [ISS]
- regulation of vasculogenesis [ISS]
- smooth muscle cell differentiation [NAS]
- tricuspid valve morphogenesis [ISS]
- umbilical cord morphogenesis [ISS]
- vascular smooth muscle cell development [IEP]
- vasculogenesis [ISS]
- ventricular cardiac muscle cell development [ISS]
- ventricular septum morphogenesis [ISS]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity [ISS]
- histone deacetylase binding [IPI]
- microsatellite binding [IDA]
- protein binding [IPI]
- protein binding transcription factor activity [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [NAS]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity [ISS]
- histone deacetylase binding [IPI]
- microsatellite binding [IDA]
- protein binding [IPI]
- protein binding transcription factor activity [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription factor binding [NAS]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A proteome-scale map of the human interactome network.
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ?30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently ... [more]
Cell Nov. 20, 2014; 159(5);1212-26 [Pubmed: 25416956]
Throughput
- High Throughput
Curated By
- BioGRID