BAIT
SHMT2
GLYA, HEL-S-51e, SHMT
serine hydroxymethyltransferase 2 (mitochondrial)
GO Process (1)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
GO Process (14)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- axon guidance [TAS]
- blood circulation [TAS]
- cell proliferation [IDA]
- cell surface receptor signaling pathway [NAS]
- collagen catabolic process [TAS]
- endothelial cell apoptotic process [IDA]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- glomerular basement membrane development [ISS]
- negative regulation of angiogenesis [IDA]
- negative regulation of cell proliferation [TAS]
- negative regulation of endopeptidase activity [NAS]
- sensory perception of sound [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
RNA-binding proteins (RBPs) determine RNA fate from synthesis to decay. Employing two complementary protocols for covalent UV crosslinking of RBPs to RNA, we describe a systematic, unbiased, and comprehensive approach, termed "interactome capture," to define the mRNA interactome of proliferating human HeLa cells. We identify 860 proteins that qualify as RBPs by biochemical and statistical criteria, adding more than 300 ... [more]
Cell Jun. 08, 2012; 149(6);1393-406 [Pubmed: 22658674]
Throughput
- High Throughput
Curated By
- BioGRID