BAIT
SHMT2
GLYA, HEL-S-51e, SHMT
serine hydroxymethyltransferase 2 (mitochondrial)
GO Process (1)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
FBXO5
EMI1, FBX5, Fbxo31, RP1-101K10.5
F-box protein 5
GO Process (10)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [TAS]
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [TAS]
- inhibition of mitotic anaphase-promoting complex activity [IDA]
- metaphase/anaphase transition of mitotic cell cycle [TAS]
- mitotic cell cycle [TAS]
- negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [IDA]
- positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- regulation of mitotic cell cycle [ISS]
- regulation of transcription involved in G1/S transition of mitotic cell cycle [TAS]
- regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
RNA-binding proteins (RBPs) determine RNA fate from synthesis to decay. Employing two complementary protocols for covalent UV crosslinking of RBPs to RNA, we describe a systematic, unbiased, and comprehensive approach, termed "interactome capture," to define the mRNA interactome of proliferating human HeLa cells. We identify 860 proteins that qualify as RBPs by biochemical and statistical criteria, adding more than 300 ... [more]
Cell Jun. 08, 2012; 149(6);1393-406 [Pubmed: 22658674]
Throughput
- High Throughput
Curated By
- BioGRID