BAIT
SHMT2
GLYA, HEL-S-51e, SHMT
serine hydroxymethyltransferase 2 (mitochondrial)
GO Process (1)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
IL18
IGIF, IL-18, IL-1g, IL1F4
interleukin 18
GO Process (24)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- MAPK cascade [IMP]
- T-helper 1 type immune response [IDA]
- angiogenesis [IDA]
- cell-cell signaling [TAS]
- cellular response to organic cyclic compound [IDA]
- chemokine biosynthetic process [TAS]
- granulocyte macrophage colony-stimulating factor biosynthetic process [TAS]
- immune response [TAS]
- inflammatory response [IDA]
- interferon-gamma biosynthetic process [TAS]
- interleukin-13 biosynthetic process [TAS]
- interleukin-2 biosynthetic process [TAS]
- lipopolysaccharide-mediated signaling pathway [IDA]
- positive regulation of NK T cell proliferation [IDA]
- positive regulation of activated T cell proliferation [IDA]
- positive regulation of granulocyte macrophage colony-stimulating factor production [IDA]
- positive regulation of inflammatory response [IC]
- positive regulation of interferon-gamma production [IDA]
- positive regulation of interleukin-17 production [IDA]
- positive regulation of natural killer cell proliferation [IDA]
- positive regulation of tissue remodeling [IC]
- regulation of cell adhesion [IDA]
- sleep [ISS]
- type 2 immune response [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
RNA-binding proteins (RBPs) determine RNA fate from synthesis to decay. Employing two complementary protocols for covalent UV crosslinking of RBPs to RNA, we describe a systematic, unbiased, and comprehensive approach, termed "interactome capture," to define the mRNA interactome of proliferating human HeLa cells. We identify 860 proteins that qualify as RBPs by biochemical and statistical criteria, adding more than 300 ... [more]
Cell Jun. 08, 2012; 149(6);1393-406 [Pubmed: 22658674]
Throughput
- High Throughput
Curated By
- BioGRID