BAIT
MOV10
fSAP113, gb110, RP11-426L16.2
Mov10 RISC complex RNA helicase
GO Process (8)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- Notch signaling pathway [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- mRNA cleavage involved in gene silencing by miRNA [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- phosphatidylinositol-mediated signaling [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
F2RL1
GPR11, PAR2
coagulation factor II (thrombin) receptor-like 1
GO Process (46)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [TAS]
- T cell activation involved in immune response [ISS]
- chemokine (C-C motif) ligand 2 secretion [IDA]
- chemokine secretion [IDA]
- defense response to virus [IDA]
- establishment of endothelial barrier [IDA]
- interferon-gamma secretion [ISS]
- interleukin-1 beta secretion [IDA]
- interleukin-10 secretion [IDA]
- leukocyte migration [IDA]
- leukocyte proliferation [ISS]
- mature conventional dendritic cell differentiation [IDA, ISS]
- negative regulation of JNK cascade [IDA]
- negative regulation of chemokine secretion [IDA]
- negative regulation of toll-like receptor 3 signaling pathway [IMP]
- negative regulation of tumor necrosis factor-mediated signaling pathway [IDA]
- neutrophil activation [IDA]
- positive regulation of ERK1 and ERK2 cascade [IDA, ISS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- positive regulation of JNK cascade [IDA]
- positive regulation of Rho protein signal transduction [IMP, ISS]
- positive regulation of actin filament depolymerization [IDA]
- positive regulation of cell migration [ISS]
- positive regulation of chemotaxis [ISS]
- positive regulation of cytokine secretion involved in immune response [IDA]
- positive regulation of cytosolic calcium ion concentration [IDA, ISS]
- positive regulation of eosinophil degranulation [IDA]
- positive regulation of glomerular filtration [ISS]
- positive regulation of interleukin-6 secretion [IDA]
- positive regulation of interleukin-8 secretion [IDA]
- positive regulation of leukocyte chemotaxis [IDA]
- positive regulation of neutrophil mediated killing of gram-negative bacterium [IDA]
- positive regulation of phagocytosis, engulfment [IDA]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISS]
- positive regulation of positive chemotaxis [IDA]
- positive regulation of pseudopodium assembly [ISS]
- positive regulation of renin secretion into blood stream [ISS]
- positive regulation of superoxide anion generation [IDA]
- positive regulation of toll-like receptor 2 signaling pathway [IMP]
- positive regulation of toll-like receptor 3 signaling pathway [IMP]
- positive regulation of toll-like receptor 4 signaling pathway [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of vasodilation [ISS]
- regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- regulation of JNK cascade [IDA]
- regulation of blood coagulation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
RNA-binding proteins (RBPs) determine RNA fate from synthesis to decay. Employing two complementary protocols for covalent UV crosslinking of RBPs to RNA, we describe a systematic, unbiased, and comprehensive approach, termed "interactome capture," to define the mRNA interactome of proliferating human HeLa cells. We identify 860 proteins that qualify as RBPs by biochemical and statistical criteria, adding more than 300 ... [more]
Cell Jun. 08, 2012; 149(6);1393-406 [Pubmed: 22658674]
Throughput
- High Throughput
Curated By
- BioGRID