ERCC6
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- DNA repair [IGI, IMP]
- activation of JNKK activity [IMP]
- activation of JUN kinase activity [IMP]
- base-excision repair [ISO]
- cellular response to DNA damage stimulus [IMP]
- intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- multicellular organism growth [IGI]
- photoreceptor cell maintenance [IMP]
- positive regulation of DNA-templated transcription, elongation [ISO]
- positive regulation of protein tyrosine kinase activity [ISO]
- pyrimidine dimer repair [IMP]
- regulation of DNA-templated transcription, elongation [ISO]
- response to UV [IMP, ISO]
- response to UV-B [IMP]
- response to X-ray [IMP]
- response to gamma radiation [IMP]
- response to oxidative stress [IMP, ISO]
- response to superoxide [IMP]
- response to toxic substance [IMP]
- transcription elongation from RNA polymerase I promoter [IMP]
- transcription-coupled nucleotide-excision repair [IMP, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
POLR1A
Gene Ontology Biological Process
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The chromatin remodeling factor CSB recruits histone acetyltransferase PCAF to rRNA gene promoters in active state for transcription initiation.
The promoters of poised rRNA genes (rDNA) are marked by both euchromatic and heterochromatic histone modifications and are associated with two transcription factors, UBF and SL1 that nucleate transcription complex formation. Active rRNA genes contain only euchromatic histone modifications and are loaded with all components of transcriptional initiation complex including RNA polymerase I. Coupled with histone acetylation and RNA polymerase ... [more]
Throughput
- Low Throughput
Additional Notes
- Figure S2
Curated By
- BioGRID