Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

Crn7 interacts with AP-1 and is required for the maintenance of Golgi morphology and protein export from the Golgi.

Rybakin V, Gounko NV, Spaete K, Hoening S, Majoul IV, Duden R, Noegel AA

Crn7 is a novel cytosolic mammalian WD-repeat protein of unknown function that associates with Golgi membranes. Here, we demonstrate that Crn7 knockdown by small interfering RNA results in dramatic changes in the Golgi morphology and function. First, the Golgi ribbon is disorganized in Crn7 KD cells. Second, the Golgi export of several marker proteins including VSV envelope G glycoprotein is ... [more]

J. Biol. Chem. Oct. 13, 2006; 281(41);31070-8 [Pubmed: 16905771]

Throughput

  • Low Throughput

Curated By

  • BioGRID