PREY
REV1
REV1L
REV1, polymerase (DNA directed)
GO Process (4)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-crystal Structure
Interaction directly demonstrated at the atomic level by X-ray crystallography. Also used for NMR or Electron Microscopy (EM) structures. If there is no obvious bait-hit directionality to the interaction involving 3 or more proteins, then the co-crystallized proteins should be listed as a complex.
Publication
XRCC1 interaction with the REV1 C-terminal domain suggests a role in post replication repair.
The function of X-ray cross complementing group 1 protein (XRCC1), a scaffold that binds to DNA repair enzymes involved in single-strand break and base excision repair, requires that it be recruited to sites of damaged DNA. However, structural insights into this recruitment are currently limited. Sequence analysis of the first unstructured linker domain of XRCC1 identifies a segment consistent with ... [more]
DNA Repair (Amst.) Dec. 01, 2013; 12(12);1105-13 [Pubmed: 24409475]
Throughput
- Low Throughput
Curated By
- BioGRID