KCNC1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
KCNC1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Differential subcellular localization of the two alternatively spliced isoforms of the Kv3.1 potassium channel subunit in brain.
Voltage-gated K(+) channels containing pore-forming subunits of the Kv3 subfamily have specific roles in the fast repolarization of action potentials and enable neurons to fire repetitively at high frequencies. Each of the four known Kv3 genes encode multiple products by alternative splicing of 3' ends resulting in the expression of K(+) channel subunits differing only in their C-terminal sequence. The ... [more]
Throughput
- Low Throughput
Additional Notes
- Kv3.1a isoform interacts with Kv3.1b isoform
Curated By
- BioGRID