BAIT
NOTCH3
CADASIL, CASIL, IMF2
notch 3
GO Process (4)
GO Function (1)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CRIP2
CRIP, CRP2, ESP1
cysteine-rich protein 2
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Notch3 Interactome Analysis Identified WWP2 as a Negative Regulator of Notch3 Signaling in Ovarian Cancer.
The Notch3 signaling pathway is thought to play a critical role in cancer development, as evidenced by the Notch3 amplification and rearrangement observed in human cancers. However, the molecular mechanism by which Notch3 signaling contributes to tumorigenesis is largely unknown. In an effort to identify the molecular modulators of the Notch3 signaling pathway, we screened for Notch3-intracellular domain (N3-ICD) interacting ... [more]
PLoS Genet. Oct. 01, 2014; 10(10);e1004751 [Pubmed: 25356737]
Throughput
- Low Throughput
Curated By
- BioGRID