FHL1
Gene Ontology Biological Process
- negative regulation of G1/S transition of mitotic cell cycle [ISO]
- negative regulation of G2/M transition of mitotic cell cycle [ISO]
- negative regulation of cell growth [ISO]
- positive regulation of potassium ion transport [ISO]
- regulation of membrane depolarization [ISO]
- regulation of potassium ion transmembrane transporter activity [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TLN1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Fhl-1, a new key protein in pulmonary hypertension.
Pulmonary hypertension (PH) is a severe disease with a poor prognosis. Different forms of PH are characterized by pronounced vascular remodeling, resulting in increased vascular resistance and subsequent right heart failure. The molecular pathways triggering the remodeling process are poorly understood. We hypothesized that underlying key factors can be identified at the onset of the disease. Thus, we screened for ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID