BAIT
MSL1
MSL-1, hMSL1
male-specific lethal 1 homolog (Drosophila)
GO Process (2)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
- MSL complex [IDA]
- nucleoplasm [IDA, TAS]
Homo sapiens
PREY
KPNB1
IMB1, IPO1, IPOB, Impnb, NTF97
karyopherin (importin) beta 1
GO Process (12)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- NLS-bearing protein import into nucleus [TAS]
- apoptotic DNA fragmentation [TAS]
- apoptotic process [TAS]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- cytokine-mediated signaling pathway [TAS]
- intracellular transport of virus [TAS]
- protein import into nucleus [IDA]
- protein import into nucleus, translocation [TAS]
- ribosomal protein import into nucleus [IDA]
- small molecule metabolic process [TAS]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage.
The stress protein p8 is a small, highly basic, unfolded, and multifunctional protein. We have previously shown that most of its functions are exerted through interactions with other proteins, whose activities are thereby enhanced or repressed. In this work we describe another example of such mechanism, by which p8 binds and negatively regulates MSL1, a histone acetyl transferase (HAT)-associated protein, ... [more]
J. Cell. Physiol. Dec. 01, 2009; 221(3);594-602 [Pubmed: 19650074]
Throughput
- Low Throughput
Curated By
- BioGRID