HIST3H3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TAF9B
Gene Ontology Biological Process
- negative regulation of apoptotic process [IMP]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IC]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of cell growth [IMP]
- protein stabilization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.
Trimethyl-lysine (me3) modifications on histones are the most stable epigenetic marks and they control chromatin-mediated regulation of gene expression. Here, we determine proteins that bind these marks by high-accuracy, quantitative mass spectrometry. These chromatin "readers" are assigned to complexes by interaction proteomics of full-length BAC-GFP-tagged proteins. ChIP-Seq profiling identifies their genomic binding sites, revealing functional properties. Among the main findings, ... [more]
Throughput
- High Throughput
Additional Notes
- H3K4me3
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| HIST3H3 TAF9B | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | 834973 |
Curated By
- BioGRID